Spravato (Esketamine) Treatment by Stella

Spravato® Treatment Near You

Proven, effective and FDA approved ketamine therapy for depressive disorder and treatment resistant depression.

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Available at Stella Boston and coming soon to Stella Chicago, along with more locations across the US.

Why Choose Spravato® for Depression

Fast and Effective

Over 75% of our patients have seen a significant reduction in depression scores. Relief often occurs within hours of treatment.

Safe and Medically Guided

Spravato® is a non-invasive treatment that has minimum risks and side effects. Each session is clinically guided by our certified providers.

Covered by Most Insurances

Spravato treatment is covered by major insurance plans. Please contact our care advocate team to verify your insurance eligibility.

FDA Approved and Covered by Insurance

For patients seeking Spravato treatment in Boston, treatment costs are covered by Blue Cross Blue Shield of MA, Mass General, Optum, Point32 and Medicare.

Coverage for additional services like intake appointments varies

What is Spravato® Treatment?

Spravato® is a treatment that provides transformative relief from depression symptoms. In a Spravato® therapy, a nasal spray form of ketamine (esketamine) is administered by certified clinical staff. Currently, it is the only FDA-approved ketamine therapy accessible to patients and is covered by most insurances.

It has shown to be one of the most promising modalities for treatment-resistant depression (TRD) in patients with major depressive disorder (MDD) with suicidal thoughts or actions. For those who have difficulty responding to other treatments like medication or therapy, Spravato® can have transformative effects and help patients break free from the cycle of depression.

How does Esketamine work?

Unlike conventional treatments like talk therapy, Esketamine therapy treats the root cause of depression symptoms, which happens on the brain's neuron level.

Esketamine is a nasal spray form of ketamine, an anesthetic that has been researched and used for many years to treat depression in clinical settings. Ketamine is a chemical that functions as an NMDA receptor antagonist that interacts with brain neurotransmitters. When ketamine is introduced into a patients' body, it works as a potent agent to increase the amount of glutamate between neurons, which then activates connections in the AMPA receptor. As a result, new neuronal growth and communication pathways are fostered, therefore creates and reconfigures brain's neuron firing patterns, making the transformation of negative thoughts possible.

Break free from depressive thoughts and symptoms

75% of our patients have shown a significant reduction in depression scores (PHQ-9) after Spravato treatment.

Explore Sparavato Treatment Near You

Spravato Treatment At Stella Center Boston

Explore Stella Boston

Coming soon to Illinois along with more locations across the US.

Spravato Cost & FAQ

What is Spravato?

Spravato is an FDA-approved variant of eketamine that is delivered intranasally. Also known by its generic name, esketamine, it is one of the two mirror-image molecules that together make up regular ketamine. Ketamine is a chemical that is used medically as an anesthetic for induction and maintenance of anesthesia. It has been also been researched and used for many years to treat depression symptoms.

Is Spravato approved by FDA?

Yes. Spravato has been approved by the Food and Drug Administration (FDA) since March 5, 2019.

What is Stella's Spravato protocol?

Stella follows the FDA-approved protocol, in sequence, the frequency of treatments will be:
- Introduction phase: Twice weekly for 4 weeks,
- Optimization phase: Once weekly for 4 weeks,
- Maintenance phase: Once every 2 weeks
- Ongoing maintenance phase: Once every 3-4 weeks if the patients' mood is stable

What symptoms and conditions does Spravato help with?

Spravato can treat symptoms of major depressive disorder (MDD), which include low mood, lack of pleasure in activities, too much or too little sleep, feelings of guilt/worthlessness/hopelessness, low energy, poor concentration, too much or too little appetite, slowing of speech or movement, and/or suicidal thinking. Especially, Spravato is indicated for treatment resistant depression (TRD), under which condition patients experience persistent depression symptoms after trying 2 or more antidepressants and talk therapy.

Who qualifies for Spravato treatment?

Spravato is FDA-approved for treatment-resistant major depressive disorder, that is, MDD that has not responded to at least two antidepressants, with adequate dose and duration. Insurance coverage varies among locations and plans. Call our care advocate team to check your insurance eligibility.

What is the difference between Spravato and IV Ketamine?

Spravato FDA-approved, and self-administered intranasally under the direction of a healthcare provider. Whereas IV ketamine is FDA-cleared for off-label use, and administered directly by a healthcare provider.

How much does Spravato treatment cost?

When covered by insurance, the co-pay for a Spravato treatment visit is comparable to that of a typical outpatient mental health visit, sometimes as low as $10 per treatment. Though the out-of-pocket cost ultimately depends on each person's specific insurance plan, deductible, etc.